Attenuated Shigella as a DNA Delivery Vehicle for DNA-Mediated Immunization
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چکیده
منابع مشابه
Live Attenuated Shigella as a Diarrheal Vaccine And/or Mucosal Delivery Vector for Dna Vaccines
Several live attenuated Shigella vaccines of different serotypes have been shown to be safe, immunogenic, and in one case effective against challenge with virulent strains. The ability to invade epithelial cells remains critical for the success of these vaccine candidates. Live, orally administered Shigella vaccine derivatives are also being evaluated as multivalent mucosal vaccines able to del...
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ژورنال
عنوان ژورنال: Science
سال: 1995
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.270.5234.299